Thanks goes out to Matt for another great suggestion. Thanks Matt!
This time its Small Can Be Big, an organization that takes 100% of every donation and applies it to a specific expense or urgent bill to help a family in need and keep them from homelessness.
They do a way better job of explaining the process on this page. But the gist is:

This is where you come in. When you lend your support to a family in need – whether it’s $3 or $300 – 100% of every penny you give goes directly toward addressing a specific family need. No middlemen. No hidden costs. No time wasted. Just an uplifting, tax-deductible gift that goes to a landlord, utility company or hospital awaiting payment.

This falls in line directly with the model of Skip a Lunch. Small donations that in masse can create change, help, or hope. Please check it out and in their words, “Help more directly, more personally, more locally, more shared.”